FIT Cancer 12 12 12th FORUM ON Translational Immunology and IMMUNOTHERAPY OF CANCER CP-05 ILT4 AND ITS R20H VARIANT AS MARKER OF POOR PROGNOSIS IN SPANISH PATIENTS WITH COLORECTAL CANCER Fernández Uría, S1; Vaquero Yuste, C1; Álvarez González, E1; Sánchez del Pueblo, C2; Suárez Solís, ML2; Mugüerza Huguet, JM2; Martín Villa, JM1; Juárez Martín-Delgado, I1 1Department of Immunology, Ophthalmology and ENT. Universidad Complutense de Madrid. Madrid. 2Hospital Clínico San Carlos. Madrid CP-06 NEOANTIGENS IN THE CROSSHAIRS: TCR THERAPY FOR CLL Martínez Soler, R1; Aran, A1; Casanovas Albertí, B1; Ramírez Chacón, A1; Tocornal Garnica, B1; García Loza, I1; Nadeu, F1; Campo, E 1; Álvarez Pérez, I2; Juan Otero, M3; González Navarro, EA3 1Fundació Clínic per la Recerca Biomèdica - Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS). Barcelona. 2Department of Cell Biology, Physiology and Immunology. Universitad Autònoma de Barcelona. Barcelona. 3Department of Immunology. Centre de Diagnòstic Biomèdic (CDB) - Hospital Clínic Barcelona. Barcelona CP-07 MPC1-MEDIATED METABOLIC REWIRING IMPROVES CANCER CELL IMMUNOGENICITY. A POSSIBLE ROLE OF MITOCHONDRIA-ENDOPLASMIC RETICULUM CONTACTS Cruz Méndez, JS1; Ruiz-iglesias, A1; Acín-Pérez, R2; Sánchez-Luengo, M3; Fernández-Aceñero, MJ4; Peregil, RM1; Uceda-González, M5; Cerdá Ferre, A5; Area-Gómez, E5; Enríquez, JA2; Mañes, S1 1Department of Immunology and Oncology. National Center for Biotechnology (CNB/CSIC). Madrid. 2GENOXPHOS Lab. Centro Nacional de Investigaciones Cardiovasculares (CNIC). Madrid. 3Flow Cytometry Unit. National Center for Biotechnology (CNB/CSIC). Madrid. 4Department of Surgical Pathology. Hospital Clínico San Carlos. Madrid. 6Center for Biological Research (CIB)-Margarita Salas. CSIC. Madrid CP-08 GENERATION OF CRISPR/CAS9-ENGINEERED ANTI-IL-13RΑ2 PD-1 DISRUPTED CAR-T CELLS Tocornal Garnica, B1; Martínez-Soler, R1; Casanovas-Albertí, B1; Ramírez-Chacón, A1; Aran, A1; Betriu-Méndez, S1; Ortiz de Landazuri, I2; Uribe, M3; Arnaldos-Pérez, C2; García-Loza, I1; Serra-Pagès, C2; Juan Otero, M2; González-Navarro, EA3 1Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). Barcelona. 2Department of Immunology. Hospital Clínic Barcelona. Barcelona. 3Department of Immunotherapy. Hospital Clínic Barcelona.Barcelona
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